hydroxymitragynine

Does Kratom Show Up As An Opiate On A Drug Test? Here’s the Truth

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The growing popularity of Kratom use leads people to ask whether drug tests would detect its presence. Standard information about kratom’s behavior in drug testing is essential both for current users and those who want to start using it.

One of the frequently asked questions is: Does kratom show out as an opiate in a drug test? This guide offers insights on science, testing procedures, screening window periods, and much more that a person should understand about selecting kratom and drug screening options.

How Does Kratom Work?

Kratom is a tree that grows in the tropical region of Southeast Asia. Leaves of its species host alkaloids, a major percentage of which are mitragynine and 7-hydroxymitragynine, which are active against opioid receptors in the brain. Kratom is a stimulant at low doses and a sedative when administered in high doses, and is used in everything but painkillers and mood boosters.

Although the effects of kratom are similar to those of opioids, kratom alkaloids are different in chemical structure from more conventional opiates such as morphine or heroin. This is relevant as far as drug testing is concerned.

Introduction to Kratom Drug Test

The increasing popularity of using kratom creates uncertainties about its appearance in drug tests. Standard drug testing procedures are commonplace in many companies that focus on safety alongside their operations. 

Current drug screening systems check for a combination of THC, cocaine, opiates, amphetamines, and benzodiazepines. Standard drug testing does not include kratom as one of its covered screening substances.

Specified tests have been developed to detect kratom along with its broken-down products. Users who must deal with drug testing during kratom usage need detailed knowledge about test types and their detection abilities.

How does Kratom work in the Body?

The use of kratom results in compounds that attach to opioid receptors located within brain tissue, especially targeting the mu receptors along with the delta and kappa receptors

The predominant alkaloid mitragynine delivers the main stimulant characteristics in kratom, but the more powerful alkaloid 7-hydroxymitragynine produces analgesic and sedative responses in the plant.

When taken, kratom travels through the body until the liver breaks it down into several metabolite components. The kidneys remove the metabolites produced from kratom metabolism, which are eliminated via urine excretion. 

The rate of kratom metabolism along with urine excretion depends upon different aspects such as user age and body weight as well as metabolic speed and personal health condition.

Types of Drug Tests and Their Detection Capabilities

Many organizations, healthcare centers, and legal institutions perform drug tests as a standard procedure. Multiple drug testing techniques have been developed to identify particular substances found in human bodily samples. 

The ability to detect various substances varies between different drug testing types, depending on their appropriate usage context.

1. Urine Tests

Among all drug testing methods, urine tests stand as the most prevalent type because they identify THC, together with cocaine and opiate compounds, along with amphetamines and benzodiazepines. 

These tests remain popular because they require no invasive methods, but they are affordable and sensitive enough to detect numerous substances.

2. Blood Tests

Blood tests require invasiveness since people do them less often than urine tests but they deliver exact drug test results. Their ability to identify substances within the bloodstream shortly after use enables their use in determining current impairment.

3. Saliva Tests

The popularity of saliva tests continues to increase because of their convenient application methods as well as their non-discriminatory testing nature. Drug detection through these tests reveals drug usage only from recent hours to days, based on the substance type.

4. Hair Tests

Hair tests maintain the widest detection capabilities because they can detect drug usage from 90 days up to long periods. The risk of hair testing remains low because of its costly nature and its complex sampling techniques.

5. Breath Tests

People use breath tests to detect the presence of alcohol in their breath as their primary purpose. Workplaces and law enforcement departments use these tests for fast responses in detecting drugs.

Another type of test for kratom detection

The chemical nature of kratom differs substantially from opiates, although it binds to brain opioid receptors in similar ways, leading to no false opiate detection in drug tests. The types of tests for kratom detection are:

1. 5-Panel Drug Tests

The 5-panel drug test functions as one of the standard drug-testing methods for detecting five distinct drugs, together with their breakdown products in human specimens. 

The test serves as a standard drug screening method that employers conduct before hiring new staff members or other organizations to verify regulatory standards.

The standard 5-panel drug test typically screens for the following substances:

  1. Marijuana (THC): This refers to the psychoactive substance found in marijuana.
  2. Cocaine: An addictive drug with tropic alkaloids obtained from the coca plant and used for enhancing one’s energy levels and focus.
  3. Phencyclidine (PCP): A hallucinogenic drug that is also known as “angel dust”.
  4. Amphetamines: This is for both the substituted amphetamines such as Adderall amphetamine and the legitimate amphetamines for instance meth or crystal meth.
  5. Opiates: This group is made of drugs that are obtained from the opium poppy and includes heroin, morphine, and codeine.

2. 10-Panel Drug Tests

Employers need to pay a higher cost for conducting the 10-panel drug test through urine analysis, and may also use blood or saliva samples. 

Essentially, this represents a typical method to detect ten particular drugs alongside their derivative substances within someone’s physiological system:

  • Amphetamines
  • Barbiturates
  • Benzodiazepines
  • Cocaine
  • Marijuana (THC)
  • Methadone
  • Opiates
  • Phencyclidine (PCP)
  • Propoxyphene
  • Quaaludes (methaqualone)

Does Kratom Show Up on Drug Tests?

When conducting standard drug screening, the test selectively screens for THC alongside cocaine and opiates, alongside amphetamines and benzodiazepines. 

Standard drug screens do not check for Kratom among their listed substances thus, standard drug tests usually cannot detect it. However, there are some considerations to keep in mind:

  • Specificity of Tests: Test procedures for standard drug detection identify particular metabolites that exist in well-known abused substances. Standard drug test panels contain no kratom or its metabolites; thus, these substances escape detection.
  • Workplace Policies: Some workplaces extend their drug screening methods with extra chemicals beyond their standard testing panels. Specialized testing protocols must be employed to detect kratom when an employer tests specifically for this substance.
  • Cross-Reactivity: Very infrequently, the compounds contained in kratom products might produce incorrect positive results for standard drug test analyses.

Does Kratom Show Up on a 10-Panel or 12-Panel Test?

  • 10-Panel Test: Kratom will not show up unless the test is specifically modified to include it. Some advanced 10-panel urine tests can detect kratom starting about 6 hours after ingestion, with detection possible for up to a week in urine.
  • 12-Panel Test: Same as above—kratom is not detected unless the test is customized for it.

Specialized Tests for Kratom Detection

These tests are more targeted and require specific analytical techniques.

1. Immunoassay Tests

Technologists can develop immunoassay-based tests that detect the kratom metabolites mitragynine and 7-hydroxymitragynine. The tests incorporate antibodies that react to metabolites in the sample, thus confirming their presence.

2. Liquid Chromatography-Mass Spectrometry 

Both instruments serve the specific purpose of detecting kratom metabolites accurately. This technique serves as an efficient method for finding low substance concentrations in multiple testing materials.

3. Gas Chromatography-Mass Spectrometry 

GC-MS functions as an extremely precise and responsive technique for confirming individual substances in testing environments. Instrumentation can accurately detect kratom metabolites and measure their concentration levels at a precise standard needed for specific laboratory testing.

Factors Influencing Kratom Detection in Drug Tests

Below are some of the most important factors that may cause kratom to appear as a substance that causes a positive drug test. These factors include:

1. Test sensitivity 

While most routine drug screenings do not directly detect kratom’s alkaloid profile, high levels of kratom or its metabolites may result in positive reactions to other opioids, including methadone.

2. Quality of ingested kratom 

Kratom can be purchased as a dietary supplement; thus, the quality of the product varies. 

3. Metabolism 

Each person’s metabolism is unique, determining how the substance will be metabolized and eliminated from the body. Based on how quickly kratom alkaloids are metabolized and cleared from the body, we understand how they may or may not show up on drug tests.

4. Dosage

Increasing kratom consumption often broadens the detection window.

5. Frequency of Use

Regular kratom use might result in prolonged detection times.

Will Kratom Make You Fail a Drug Test?

Kratom will not make you fail a standard drug test for opiates or other common substances. However, if a test specifically screens for mitragynine or 7-hydroxymitragynine, you could test positive for kratom use.

Kratom False Positives: Is It Possible?

False positives for opiates due to kratom use are very rare but have been reported. In rare cases, kratom’s alkaloids may cause a false positive for methadone or other opioids because of the way they interact with opioid receptors. 

If you use kratom and receive a positive result for opiates, request a confirmation test such as GC-MS and disclose your kratom use to the testing facility.

Kratom and DOT Drug Screens

DOT drug screens do not test for kratom. These tests focus on federally regulated substances like marijuana, cocaine, opiates, amphetamines, and PCP. Unless the DOT or employer specifically adds kratom to the panel, it will not be detected.

How Long Does Kratom Stay in Your System?

Detection of kratom in your body depends on multiple factors, including the amount you take, how often you consume it, personal metabolic rates, and what kratom product you choose to use. 

Under normal conditions, the two main kratom compounds, mitragynine and 7-hydroxymitragynine, stay active in the body for 7 to 9 hours. Individual differences create major impacts on the time necessary for detecting kratom in the body.

Urine testing of kratom detects the substance for periods ranging from 5 to 7 days for infrequent users. The detection period increases in regular kratom users because their bodies store kratom metabolites. 

Blood tests identify kratom usage for only short periods, extending to a few days since the last consumption, whereas kratom detection is less prevalent in these tests. 

Saliva tests can identify kratom immediately, followed by blood tests that process kratom within 24 hours, but hair tests have a lower chance of success in detecting kratom use because they examine hair for up to 90 days.

Final Thoughts

Kratom’s unique chemistry means it does not show up as an opiate on most drug tests. Standard 5-panel, 10-panel, and DOT drug screens do not detect kratom unless they are specifically modified to do so. While rare, false positives can happen, so always communicate openly with your testing provider if you use kratom. 

As kratom’s legal and regulatory status evolves, more targeted testing may become common in certain settings, but for now, most routine drug screens will not detect kratom use.

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